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EDUCATION
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1984 B.S. in
Biology, Georgetown University, Washington DC
1988 MD, Georgetown University Medical School, Washington DC
POSTDOCTORAL
TRAINING
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1988 - 1989
Intern in Medicine, University of Massachusetts Medical
Center, Worcester MA.
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1989 - 1990
Junior Medical Resident, University of Massachusetts Medical
Center, Worcester MA.
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1990 - 1991
Senior Medical Resident, University of Massachusetts Medical
Center, Worcester MA.
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1991 - 1992 Chief
Medical Resident, University of Massachusetts Medical Center,
Worcester MA.
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1992 - 1996
Research and Clinical Fellow in Medicine (Cardiology), Harvard
Medical School and the Beth Israel Hospital, Boston MA.
LICENSURE AND
CERTIFICATION
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1990 -
Massachusetts State License for Medicine and Surgery
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1991 - Diplomate
- American Board of Internal Medicine
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1995 - Diplomate
- American Board of Internal Medicine, Cardiovascular Disease
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1996 - New York
State License for Medicine and Surgery
EMPLOYMENT
1996 - Invasive/Interventional Cardiologist, S.J.H.
Cardiac Catheterization Associates, P.C., Syracuse, NY.
ACADEMIC
APPOINTMENTS
1991 - 1992 Instructor in Medicine, University of
Massachusetts Medical School, Worcester MA.
1995 - 1996 Instructor in Medicine, Harvard Medical School,
Boston MA.
1998 - Assistant Clinical Professor of Medicine, State
University of New York Health Science Center.
HOSPITAL/CLINICAL APPOINTMENTS
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1989 - 1992
Primary Care Physician, Evening Medical Clinic, Tri - River
Family Health Center, Uxbridge MA.
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1990 - 1992
Attending Physician, Emergency Room, Worcester Hahneman
Hospital, Worcester MA.
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1991 - 1992
Urgent Care Attending Physician, Urgent Care Center, Holden
Hospital, Holden MA.
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1992 - 1993 In
House Physician, Special Care Unit, Marlborough Hospital,
Marlborough MA.
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1992 - 1996
Clinical Fellow, Beth Israel Hospital, Boston MA.
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1993 - 1994 In
House Physician, Intensive Care Unit, Winthrop Hospital,
Winthrop MA.
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1994 - 1996 In
House Physician, Melrose - Wakefield Hospital, Melrose MA.
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1996 - Attending
Invasive Cardiologist, Cardio Lab, St. Joseph's Hospital,
Syracuse, N.Y.
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1996 - Attending
Invasive Cardiologist, Cardiac Catheterization Laboratory,
Crouse Medical Center, Syracuse, N.Y.
MAJOR
COMMITTEE ASSIGNMENTS
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1988 - 1992
Executive Residency Committee, University of Massachusetts
Medical Center, Worcester MA.
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1991 - 1992
Resident Selection Committee, University of Massachusetts
Medical Center, Worcester MA.
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1991 - 1992
Pharmacy Committee, University of Massachusetts Medical
Center, Worcester MA.
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1991 - 1992
Medical Quality Assurance Committee, University of
Massachusetts Medical Center, Worcester MA.
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1991 - 1992
Housestaff Implementation Committee, Milford Hospital, Milford
MA.
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1991 - 1992 Co -
Chairman, Medical Journal Club Committee, University of
Massachusetts Medical Center, Worcester MA.
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1996 -
Cardiothoracic Surgery Committee, St. Joseph's Hospital,
Syracuse N.Y.
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1999 -
Investigational Review Board, St. Joseph's Hospital, Syracuse
NY.
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1999 -
Representative to the Cardiovascular Advisory Committee,
Medical Society of the State of New York
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1999 - Editorial
Consultant, Catheterization and Cardiovascular Interventions
(Journal of the Society for Cardiac Angiography and
Interventions)
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2000 -
Catheterization Laboratory Committee, Crouse Hospital,
Syracuse N.Y.
ORGANIZATIONS
AND SOCIETIES
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1988 - 1998
Massachusetts Medical Society
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1988 - 1992
Worcester District Medical Society
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1991 - Member,
American College of Physicians.
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1992 - 1996
Norfolk County Medical Society
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1993 - Member,
American Heart Association
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1996 - Member,
Medical Society of the State of New York
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1996 - Member,
Onondaga County Medical Society
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1997 - Member,
Society for Coronary Angiography and Intervention
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1997 - Fellow,
American College of Cardiology
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2000 - Fellow,
Society for Cardiac Angiography and Interventions
MAJOR
ADMINISTRATIVE RESPONSIBILITIES
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1993 Co -
Director, Core Angiographic Laboratory, Thrombolysis in
Myocardial Infarction (TIMI) - 9 Study, Beth Israel Hospital,
Boston, MA.
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1993 Co -
Investigator, Thrombolysis in Myocardial Infarction (TIMI) - 8
Study, Beth Israel Hospital, Boston, MA.
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1996 Co -
Director Interventional Cardiology Research, St. Joseph's
Hospital, Syracuse, N.Y.
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1997 Principle
Investigator, EXTRA Study, St. Joseph's Hospital, Syracuse,
N.Y.
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1998 Principle
Investigator, Beta - Cath Study, Crouse Hospital, Syracuse,
N.Y.
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1999 Principle
Investigator, START study, Crouse Hospital, Syracuse, N.Y.
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2000 Principle
Investigator, PREDICT Study, St. Joseph's Hospital, Syracuse,
N.Y.
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1999 Principle
Investigator, SAFER Study, St. Joseph's Hospital, Syracuse,
N.Y.
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2000 Principle
Investigator, RAPIER Study, St. Joseph's Hospital, Syracuse,
N.Y.
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2001 Principle
Investigator, SWING Study, St. Joseph's Hospital, Syracuse
N.Y.
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2001 Principle
Investigator, SPLASH Study, St. Joseph's Hospital, Syracuse
N.Y.
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2001 Principle
Investigator, SIRIUS Study, St. Joseph's Hospital, Syracuse
N.Y.
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2001 Principle
Investigator, FIRE Filterwire Study, St. Joseph's Hospital,
Syracuse N.Y.
BUSINESS
INTERESTS
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1999 - Chairman,
Head of Scientific Development and founding partner of
AngioLink Co. This private company, based in Stoughton MA, is
dedicated to assisting physicians in new product development,
specifically; refining concepts, engineering and design,
patent and legal support, prototype development, pre-clinical
and clinical testing, marketing and sales. Mainly focused in
the fields of interventional cardiology, peripheral vascular
intervention and cardiothoracic surgery.
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2001 - Medical
Advisory Board, Boston Scientific Company, Natick MA.
MAJOR
RESEARCH INTERESTS
1. Utilization of
intracoronary ultrasound for optimal percutaneous coronary
revascularization in humans (includes participation in the OARS
and RAVES multicenter studies).
2. Multicenter studies utilizing new techniques for percutaneous
coronary revascularization (TIMI - 3, TIMI - 4, TIMI - 8, TIMI -
9, STRESS, OARS, RAVES, STRATUS, DART, VEGAS, NIRVANA, EXTRA,
CADILLAC, SPORT, Beta Cath, START, PREDICT, SAFER, RAPIER,
Filterwire).
3. Feasibility and efficacy of primary PTCA for the treatment of
acute myocardial infarction (Author, Primary Angioplasty section
of Cardiology- Up to Date, Stent PAMI and CADILLAC trials,
created primary PTCA quality assurance program at St. Joseph's
Hospital, Syracuse N.Y.).
4. Clinical trials investigating new stent designs (EXTRA,
NIRVANA, NIRON, PREDICT, SIRIUS, VISION).
5. Transradial Catheterization - applicability to patient
subsets, clinical outcomes etc.
6. Development of hemostasis devices applied to percutaneous
vascular access.
PUBLICATIONS
Original Reports
1. Caputo RP, Carrao J, Lew R, Becker RC. Effect of serum
cholesterol on hemorrhagic complications following thrombolytic
therapy for acute myocardial infarction. Cardiology
1991;79:211-218.
2. Becker RC, Caputo RP, Ball S, Corrao JM, Baker S, Gore JM.
Hemorrhagic potential
of combined diltiazem and recombinant tissue-type plasminogen
activator administration. Am Heart J 1993;126:11-14.
3. Caputo RP, Cohen DJ, Baim DS, Kuntz RE. Extravasation of
Thrombus into the
aortic root: A complication following the use of an infusion
catheter for intra-graft thrombolysis. Catheterization and
Cardiovascular Diagnosis. 1995
4. Caputo RP, Chafizedeh E, Stoler R, Lopez J, Cohen DJ, Kuntz
RE, Carrozza JP,
Baim DS. Stent Jail: A minimum security prison. Am J Cardiol
1996;77:1226-1230.
5. Sukin C, Baim DS, Caputo RP, Ho KKL, Laham R, Flatley M,
Carrozza JP, Cohen DJ. The impact of optimal stenting techniques
on cardiac catheterization laboratory resource utilization and
costs. Am J Cardiol 1997;79:275-280.
6. Lopez JJ, Ho KKL, Stoler R, Caputo RP, Carrozza JP, Kuntz RE,
Baim DS, Cohen DJ. Percutaneous treatment of protected and
unprotected left main coronary stenoses with new devices:
Immediate angiographic results and intermediate-term follow up.
J Am Coll Cardiol 1997;29:345-352.
7. Caputo RP, Ho KKL, Stoler R, Sukin C, Lopez JJ, Cohen DJ,
Kuntz RE, Berman A, Carrozza JP, Baim DS. Effect of continuous
quality improvement analysis on the delivery of primary
percutaneous transluminal coronary angioplasty for acute
myocardial infarction. Am J Cardiol 1997;79:1159-1164.
8. Lopez JJ, Edelman ER, Stamler A, Hibberd MG, Pottumarthi P,
Caputo RP,
Carrozza, JP, Douglas PS, Sellke FW, Simons M. Basic fibroblast
growth factor in a porcine model of chronic myocardial ischemia:
A comparison of angiographic, echocardiographic and coronary
flow parameters. J Pharm and Exp Therapeutics 1997;282:385-390.
9. Sukin CA, Baim DS, Caputo RP, Ho KKL, Laham RJ, Flately MG,
Carrozza JP, Cohen DJ. The impact of optimal stenting techniques
on cardiac catheterization laboratory resource utilization and
costs. Am J Cardiol 1997;79:275-280.
10. Caputo RP, Rosenberg J, Fedele K, Giambartolomei A.
Myocardial ischemia resulting from spontaneous dissection in a
patient with massive bilateral sinus of valsalva aneurysms.
Cathet and Cardiovasc Diagn 1999;47:194-198.
11. Simons AJ, Caputo RP, Esente P, Giambartolomei A, Bowser M,
Reger M, Walford G. An unusual complication during deployment of
a Multi-Link stent. Cathet and Cardiovasc Diagn 1999;47:58-60.
12. Caputo RP, Simons A, Giambartolomei A, Grant W, Fedele K,
Esente P. Transradial cardiac catheterization in patients with
prior brachial artery cutdown. Cathet and Cardiovasc Diagn
1999;48:271-274.
13. Caputo RP, Amin N, Marvasti M, Wagner S, Levy C,
Giambartolomei A. Percutaneous treatment of a saphenous vein
graft perforation with and autologous vein covered stent. Cathet
and Cardiovasc Diagn 1999;48:382-386.
14. Caputo RP, Abraham S, Churchill D. Transradial coronary
stent placement in a patient with severe idiopathic autoimmune
thrombocytopenic purpura. J Invas Cardiol 2000; 12:365-368.
15. Caputo RP, Simons A, Giambartolomei A, Grant W, Fedele K,
Abraham S, Reger MJ, Walford GD, Esente P. Transradial cardiac
catheterization in elderly patients. Cathet and Cardiovasc
Intervent 2000; 51:287-290.
16. Caputo RP, Simons AJ, Giambartolomei A, Grant W, Fedele K,
Abraham S, Felice P, Reger MJ, Walford GD, Esente P. Safety and
Efficacy of Repeat Transradial Access for Cardiac
Catheterization Procedures. Cathet Cardiovasc Intervent
2001;54:188-190.
17. Caputo RP, Giambartolomei A, Simons AJ, Reger MJ, Wagner S,
Esente P.
Use of Combination Glycoprotein IIb/IIIa inhibitor and Direct
Thrombin Inhibitor Drugs to Support Percutaneous Coronary Stent
placement in a Patient with Renal Insufficiency and Heparin
Induced Thrombocytopenia. J Invas Cardiol 2001;13:657-659.
18. Baim DS, Flately M, Caputo RP, O'Shaughnessy C, Low R,
Fanelli C, Popma J, Fitzgerald P, Kuntz R. Comparison of
Predilatation vs. Direct Stenting in Coronary Treatment using
the Medtronic AVE S670 Coronary Stent System (The Predict
Trial). Am J Cardiol. 2002; 88: 1364-1369.
19. Cutlip DE, MD, Ricciardi, MJ MD, Carrozza JP, MD, Giri S,
MD, Dua V, MD, Garringer J, MD, Ling FS, MD, Caputo RP, MD. A
Randomized Comparison of Standard Primary Angioplasty To
Facilitated Primary Angioplasty with Early Tirofiban
Administration in the Emergency Room. Am Heart J. 2001 (in
press)
Abstracts
1. Caputo RP, Corrao J, Lew R, Becker RC. The effect of
serum cholesterol on hemorrhagic complications following rt-PA
administration. Blood 1990;76:1649a.
2. Caputo RP, Becker RC. Environmental tobacco smoke as a risk
factor for coronary heart disease: Assessment of health beliefs
and practices in medical students and resident physicians. Third
Annual American Heart Association Massachusetts Affiliate
Cholesterol Conference, February 1992.
3. Becker RC, Caputo RP, Ball S, Corrao J, Ansell J, Baker S,
Gore J. Hemorrhagic potential of combined intravenous diltiazem
and tissue plasminiogen activator administration. J Am Coll
Cardiol 1993;21(2):397A.
4. Paik GY, Caputo RP, Nunez BD, Baim DS, Carrozza JP. Thrombus
contains soluble factors which decrease blood flow in swine
coronary arteries through a nitric oxide-dependent pathway. J Am
Coll Cardiol 1994;23:64A.
5. Wood MJ, Cohen DJ, Laham RJ, Caputo RP, Carrozza JP, Lopez JJ,
Baim DS. Catheter based revascularization in patients with prior
coronary bypass surgery - increasing prevalence and new device
use in 1993 compared to 1988. Circulation 1994;90(4):I63.
6. Caputo RP, Kuntz RE, Baim DS, Carrozza JP. Balloon
counterpulsation in the ascending aorta provides greater
coronary blood flow compared with descending counterpulsation.
Circulation 1994;90(4):I604.
7. Caputo RP, Lopez JJ, Ho KKL, Paik GY, Kuntz RE, Baim DS,
Carrozza JP. Intravascular ultrasound analysis of routine high
pressure balloon post-dilatation after Palmaz-Schatz stent
deployment. J Am Coll Cardiol 1995;49A.
8. Caputo RP, Ho KKL, Lopez JJ, Stoler RC, Cohen DJ, Carrozza
JP. Quantitative angiographic comparison of Palmaz-Schatz stent
implantation with and without intravascular ultrasound.
Circulation 1995;92(8):I545.
9. Sukin CA, Caputo RP, Laham RJ, Carrozza JP, Cohen DJ.
Catheterization laboratory
resource utilization and costs for Palmaz-Schatz native coronary
artery stenting in 1995 vs STRESS. Circulation 1995;92(8):I661.
10. Lopez JJ, Starebier A, Edelman ER, Hibberd MG, Caputo RP,
Carrozza JP, Prasad PV, Douglas PS, Sellke FW, Simons M. Local
bFGF treatment results in angiographic collateral development,
dose related increase in coronary flow and myocardial function
in chronic myocardial ischemia. Circulation 1995;92(8):I67.
11. Lopez JJ, Caputo RP, Ho KKL, Stoler R, Carrozza JP, Kuntz
RE, Baim DS, Cohen DJ. Percutaneous treatment of left main
coronary stenoses with new devices: Acute results and
intermediate term follow-up. Circulation 1995;92(8):I147.
12. Carrozza JP, Kereiakas D, Caputo RP, Knopf WD, Nolan K,
Chase K, Chen X,
Senerchia C, Rodriguez O, Cutlip D.P. Final acute, 30-day, and
6-month clinical and angiographic outcome from the multicenter,
randomized EXTRA trial comparing the operator-mounted XT and
Palmaz-Schatz coronary stents. Circulation 1998;17:I661.
13. Caputo RP, Giambartolomei A, Simons A, Esente P, Keriakes D,
Ho KKL, Carrozza JP. Small vessel stenting - Comparison of
modular vs. slotted tube design. Six month results from the
EXTRA Trial. J Am Coll Cardiol 2000;35(2):56A.
14. Shimodozona, Honda Y, Caputo RP, O'Shaughnessy CD, Low RL,
Rutherford BD,Zetterlund PC, Rogers, CDK, Yock PG, Baim DS,
Fitzgerald PJ. Acute and chronic vessel responses to direct
stenting vs. stenting with predilatation: A serial intravascular
ultrasound study. J Am Coll Cardiol 2001;37:26A.
15. Caputo RP, A. Ebner, G. Kanner, K. Eliasen, S. Tallarida, T.
Piemonte, S. Bollinger Percutaneous Femoral Arteriotomy Repair -
Initial Experience with a Novel Staple Closure Device. J Am Coll
Cardiol 2001;88(5A):33G.
16. Rinaldi MJ, Piana RN, Caputo RP, Gordon PC, Lopez JJ,
Dauerman HL, Hammes LN, Holmes DR, Shaikh SR, Ryan TJ, Warner JJ,
Zidar JP, Kiernan FJ, Moussa I, Palacios IF, Cox DA, Lim J,
Murphy S, Cutlip DE, Ho KKL, Gibson M, Cohen DJ. Multicenter
Study of Stent Thrombosis in the Modern Era. J Am Coll Cardiol
2001;88(5A):4G.
Book Chapters
1. Caputo, RP. Acute Heart Failure. In Irwin RS, Cerra FB, JM
Rippe (eds): Intensive Care Medicine 4th Edition, Philadelphia,
PA: Lippencott - Raven, 1999, pp 413 - 428.
2. Caputo, RP. Primary Angioplasty. In Podrid P (ed): Cardiology
UpToDate, Wellesley MA, 1999.
3. Caputo RP, Grossman W. Brachial Cutdown Approach. In Baim DS,
Grossman W (eds): Cardiac Catheterization, Angiography, and
Intervention 6th Edition, New York, NY: Williams & Wilkins,
2000, pp101 - 124.
4. Caputo RP, Becker RC. Acute Heart Failure. In Irwin RS, Rippe
JM (eds): Munual of Intensive Care Medicine 3rd Edition, New
York, N.Y.: Lippincott Williams & Wilkins, 2000, pp171 - 176.
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